If we cover a lot of numbers, we expose many numbers "to zero", but zero is a playable slot, it is not zero, we can stake at all numbers and be sure to lose one, we can leave one slot empty and break even or lose. In other world it is not the number of slots, it is the pay out rules. An American wheel has 38 slots, and if it paying fair odds it can be a good choice.
A nozero wheel has 36 slots, and an American wheel using payout 38 can be better to use, if we cover a lot of numbers. Fair odds do not expose a wide bet to HE, so HE it has no issue at such table.
When we bet on many numbers (almost all), we want not to hit a specific number, we want to avoid one or a few more, we win if one or two numbers MISS. If we bet all except one number, we benefit using a wheel with so many slots as possible, if the odds are fair. Can we spot cold numbers we win.
And we can find an AM wheel paying 38 units on a plein, which gives 2/38 Chance of hitting an unwanted number,
an a NOZ it is 2/36. With the right betting we will never lose all chips on the table, in one spin, rather just a few.
The same goes for the play I wrote about in an other thread, if we use EC for covering. (IE we bet 18 on low instead of plein) a fair odds zero wheel pay back the money, and if we have chip on zero we get full pay on zero and all on the EC back.